Approaches to Calculating Number Needed to Treat (NNT) with Meta-Analysis

Here, we have demonstrated three different methods for calculating NNT with meta-analysis data. I learned a lot from this experience, and I hope you find it enjoyable and informative as well. Thank you, @wwrighID, for initiating the discussion and providing a pivotal example by using the highest weight control event proportion to back-calculate ARR and, eventually, NNT. I also want to express my gratitude to @DrToddLee for contributing a brilliant method of pooling a single proportion from the control group for further estimation. Special thanks to @MatthewBJane, the meta-analysis maestro, for guiding me toward the correct equation to calculate event proportions, with weight estimated by the random effect model. 🙏

#IDWeek2023 Posts/Tweets Analysis

Immersed in gratitude and inspiration at #IDWeek2023 🌐! A massive thank you to everyone who contributed - your posts were a beacon of warmth and wisdom. 🌟 Celebrating the triumphs of award recipients 🏆, your remarkable achievements propel us all forward! Enlightened by the groundbreaking insights from new trials, we are reminded to remain humble and passionate in our continuous quest for knowledge. Together, we will continue unveiling the realms of Infectious Disease, advancing with unity and purpose!

An Educational Stroll With Stan - Part 4

What an incredible journey it has been! I’m thoroughly enjoying working with Stan codes, even though I don’t yet grasp all the intricacies. We’ve already tackled simple linear and logistic regressions and delved into the application of Bayes’ theorem. Now, let’s turn our attention to the fascinating world of Mixed-Effect Models, also known as Hierarchical Models

An Educational Stroll With Stan - Part 3

Diving into this, we’re exploring how using numbers to express our certainty/uncertainty, especially with medical results, can help sharpen our estimated ‘posterior value’ and offer a solid base for learning and discussions. We often talk about specifics like sensitivity without the nitty-gritty math, but crafting our own priors and using a dash of Bayes and visuals can really spotlight how our initial guesses shift. Sure, learning this takes patience, but once it clicks, it’s a game-changer – continuous learning for the win!

An Educational Stroll With Stan - Part 2

I learned a great deal throughout this journey. In the second part, I gained knowledge about implementing logistic regression in Stan. I also learned the significance of data type declarations for obtaining accurate estimates, how to use posterior to predict new data, and what generated quantities in Stan is for. Moreover, having a friend who is well-versed in Bayesian statistics proves invaluable when delving into the Bayesian realm! Very fun indeed!